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Prof. Radka ArgirovaПроф. д.м.н. Радка Аргирова, вирусолог, Аджъбадем Сити Клиник ДКЦ и Токуда Болница, София

Преди да  опишем особеностите в специфичната диагностика на HIV-инфекцията,  ще дефинираме някои основни понятия от областта HIV/СПИН. HIV-инфекцията се определя като периодът от момента на заразяване с HIV до смъртта при естествен ход на инфекцията. СПИН е последната фаза на HIV инфекцията, като съществуват ясно определени критерии – клинични и лабораторни -  за поставяне на диагнозата  СПИН. Симптомите на остра/ хронична HIV инфекция при възрастни и деца са описани в Приложение 1 към чл.10,т.1 на Наредба N 47 на МЗ, обнародвана в ДВ, бр.103/29.12.2009 г.  В Приложение 2 към чл.10,т.2 на същата Наредба са описани индикаторните заболявания за СПИН.
Прозоречен период е времето между заразяването с HIV и появата в кръвта на биохимично измерими маркери на инфекцията (най-често  антитела, но като маркери могат да бъдат използвани и вирусспецифични антигени, както и вирусна РНК). Сероконверсия е моментът, в който се откриват биохимично измеримите маркери (най-често антитела към HIV, които най-вероятно се формират по-рано, отколкото се откриват). Практически, прозоречният период е времето между заразяването и откриването на антивирусните антитела. HIV антителата се откриват най-рано 2 седмици след заразяването, в 60-65% от случаите се откриват след 4 седмици, в 80% - след 6 седмици, в 90% - след 8 седмици и в 95-98% - след 12 седмици. При съвременните тестове от 4-то поколение освен анти-р24 антителата, се открива и р24 антигена – около 4-5 дни преди появата на антителата. Най-ранно определимият лабораторен маркер е HIV РНК, която пък се открива около 6-7 дни преди р24 антигена. Следователно, няма никакъв смисъл да се търсят специфични маркери на HIV преди началото на втората седмица след заразяването.



Latest news

BFPA starts working on a new project – ARIE - supported by the ERASMUS+ program

Sofia, March 2021

The Bulgarian Family Planning and Sexual Health Association (BFPA) is a partner in the first European project that encourages People Living with HIV (PLHIV) to implement regularly a system of aerobic exercises. The project was supposed to start in the beginning of 2020 but the Covid-19 pandemic postponed the start with one year. So ARIE will be implemented in 2021 and 2022, coordinated by ANLAIDS Lombardia  - an organization that was a partner of the Association under other projects  - for HIV  prevention, for creating an online informational system for Hepatitis B and C and for cervical cancer prevention. We are partners from  6 countries (Italy, Bulgaria, Greece, Lithuania, Romania and Slovenia), 7 organizations and over 30 experts. ARIE is an ambitious project to encourage participation in sports and physical activity of people living with the HIV infection and are on therapy, in line with EU recommendations and guidelines on physical activity.
The project intends to promote physical activity in the form of personalized paths, among people aged between 18 and 50 who live with HIV infection and who are under treatment, offering an innovative fitness protocol, and in order to involve them in moderate physical activity. Therefore, the project through the development of the protocol aims to promote voluntary activities in sport, together with awareness of the importance of physical activity for the benefit of health through greater participation in sport for all.
Online Meeting of LAP in Seeking Different Approaches to Work with Young People

Sofia, February 24, 2021

Another online meeting of Learning Action Partnership (LAP) took place on February 24th, 2021. The participants – guest colleagues from Center for Study of Democracy (CSD); representatives of BFPA, Know How Center for Alternative Care of NBU, BYRC, SAPI, Re-Act Association, ASC Foundation, NNHM and IOM – reviewed the progress of implementation of the so called ‘small projects’ in the frame of LAP. The short video representing the work of LAP was discussed and approved for use.
The special guests of the online meeting presented the campaign ‘Find Another Way’, directed against radical messages and actions of young people in internet. Safe Internet Center and Center for Study of Democracy, worked on the initiative for three years, presented results and conclusions from their online communicational campaign.
The main target groups of the project were young people 14-19 in Bulgaria. Their main goal – prevention of violence, connected with the extreme-right messages and reducing the vulnerability of young people towards extreme-right messages and propaganda. From CSD strived to work for reducing anti-minority attitudes and messages and violence against minority groups, they tried to present other, different points of view and to involve young people in constructive alternative causes via narratives for stimulating critical thinking and identifying fake messages.

A new project “Youth Voices, Youth Choices” of the Bulgarian Association for Family Planning and Sexual Health has been launched

Sofia, February 8-10, 2021

The first online meeting of the project “Youth Voices, Youth Choices” was held on February 8-10, 2021. The project "Youth Voices, Youth Choices" (2021-2023) is a 30-month international project implemented in Bulgaria by the Bulgarian Family Planning and Sexual Health Association (BFPA). Partner organizations from Albania, BiH, Kosovo and Northern Macedonia will implement similar initiatives in their countries. The project is implemented with the coordinative role of the International Planned Parenthood Federation with the support of the programme for socially responsible business of the company MSD and aims to create more accessible and youth-friendly SRH services and information, paying special attention to the most vulnerable groups.