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Prof. Radka ArgirovaПроф. д.м.н. Радка Аргирова, вирусолог, Аджъбадем Сити Клиник ДКЦ и Токуда Болница, София

Преди да  опишем особеностите в специфичната диагностика на HIV-инфекцията,  ще дефинираме някои основни понятия от областта HIV/СПИН. HIV-инфекцията се определя като периодът от момента на заразяване с HIV до смъртта при естествен ход на инфекцията. СПИН е последната фаза на HIV инфекцията, като съществуват ясно определени критерии – клинични и лабораторни -  за поставяне на диагнозата  СПИН. Симптомите на остра/ хронична HIV инфекция при възрастни и деца са описани в Приложение 1 към чл.10,т.1 на Наредба N 47 на МЗ, обнародвана в ДВ, бр.103/29.12.2009 г.  В Приложение 2 към чл.10,т.2 на същата Наредба са описани индикаторните заболявания за СПИН.
Прозоречен период е времето между заразяването с HIV и появата в кръвта на биохимично измерими маркери на инфекцията (най-често  антитела, но като маркери могат да бъдат използвани и вирусспецифични антигени, както и вирусна РНК). Сероконверсия е моментът, в който се откриват биохимично измеримите маркери (най-често антитела към HIV, които най-вероятно се формират по-рано, отколкото се откриват). Практически, прозоречният период е времето между заразяването и откриването на антивирусните антитела. HIV антителата се откриват най-рано 2 седмици след заразяването, в 60-65% от случаите се откриват след 4 седмици, в 80% - след 6 седмици, в 90% - след 8 седмици и в 95-98% - след 12 седмици. При съвременните тестове от 4-то поколение освен анти-р24 антителата, се открива и р24 антигена – около 4-5 дни преди появата на антителата. Най-ранно определимият лабораторен маркер е HIV РНК, която пък се открива около 6-7 дни преди р24 антигена. Следователно, няма никакъв смисъл да се търсят специфични маркери на HIV преди началото на втората седмица след заразяването.



Latest news

Social and health messages in Roma neighbourhoods through theatre

Sofia, July 31, 2019

On the last day of July the Roma neighbourhood Fakulteta in Sofia was visited by William Shakespeare and Miguel de Servantes. We started with the best – Romeo and Juliet and Don Quixote. The Roma actress Natalia Tzekova staged a funny and educational performance with the participation of talented children and youth from the neighborhood in which the art was intertwined with social and health related messages. Romeo and Juliet demonstrated the benefits of family planning, contraception and health education and spoke in verse about the harm of school dropout, early marriages and children having children. The participants performed short sketches which contained the same messages, debunked myths and demonstrated how powerful personal example is. Don Quixote explained some of the community specificities which started a short discussion on stage who should take example from whom about health and health prevention. In between sketches and play scenes the participants shared their own personal stories about health and family planning. At the end of the play as a recap of what was presented they raised a few banners with messages on the same topic”: “I have dreams and goals”, “I am not an incubator for babies”, “Ask – someone will tell you”. The audience appreciated the messages and the element of humor in the sketches and play scenes.

The alumni of the first Health Education Academy graduated successfully

Sofia, June 17, 2019

Monday, June 17th. Our first alumni class of the Sofia Health Education Academy demonstrated their skills and knowledge in front of classmates, teachers, school directors, school psychologists, parents and supporting institutions. The solemn event took place in the Events Hall at 1st High school, Sofia. The young people from 1st, 144th, 119th schools, 1st ELS and the Professional School of Textile and Fashion Design split into three teams after “drawing straws” and presented the topics “Transformations During Puberty”, “Contraception and STIs” and “Prevention of addictions”. We are very glad that our video on puberty was part of the “fun”. Otherwise the presentations pushed the audience to participate actively. The culmination was a surprise for all – we were visited by the TV show “Masters of the air” who enhanced the effect of the challenge.

BFPA gathered the teams from Sofia, Yambol and Montana on a work meeting

Varshetz, May 10-12, 2019

From May 10th trough 12th in Varshetz, BFPA held a working meeting under the “My Body, my rights” project, funded as a part of the global “MSD for Mothers” programme. Hosts and speakers at the meeting were Dr. Radosveta Stamenkova, Ventzislav Kirkov and Boyan Mladenov form the BFPA team in Sofia, and the participants were the local project coordinators, health mediators and social workers from the project locations: Yambol – the villages of Kukorevo, Hadjidimitrovo, Veselinovo and Zavoy; Montana – Ogosta and Kosharnik districts; Sofia –Fakulteta and Filipovci districts. During the working meeting were discussed theoretical and real practice cases from field work with representatives of marginalized groups on topics like hygiene, health messages and campaigns, STI prevention, family planning and contraception. The people working in the project locations shared their experience from this and preceding projects about field work with marginalized groups, they discussed what are the challenges and the most successful approaches for achieving the best results. Peter Tzvetanov, coordinator of project activities in Montana, presented a memorable educational session on self-help groups and his colleagues from Montana and Yambol re-enacted some interesting practical cases. Their colleagues from Sofia put up for discussion theoretical situations that may arise during work.